Monthly Archives: April 2016

A comprehensive comparison of tools for differential ChIP-seq analysis

This recent paper deals with the “space of infinite possibilities” of ChIP-Seq data analysis, focusing on challenges of differential binding analysis. They have underlined multiple challenges in this area (Introduction, page 2) and compared 14 software packages, using both real-world and simulated datasets. The observed differences between the results obtained with different methods were not… Read More »