Category Archives: Gene Expression

omictools.com: Search engine for biological data analysis

Re: omictools.com Finding software that is relevant to any biological analysis can be inspired by reading a paper or perhaps searching within Google. The web site https://omictools.com/ contains 16,971 software (omic) tools that are organized in categories shown on the home page. Checking a bit further one can find interesting entries such as: High-throughput sequencing data analysis…… Read More »

A comprehensive comparison of tools for differential ChIP-seq analysis

This recent paper deals with the “space of infinite possibilities” of ChIP-Seq data analysis, focusing on challenges of differential binding analysis. They have underlined multiple challenges in this area (Introduction, page 2) and compared 14 software packages, using both real-world and simulated datasets. The observed differences between the results obtained with different methods were not… Read More »

Shoots, roots and mobile sRNA-related epigenetics

Last week PNAS has published something which would apparently contribute to future textbooks: Mobile small RNAs regulate genome-wide DNA methylation. You think that cutting / physical joining of different plants (grafting) will leave their genomes unaffected, right? Think twice! Authors show that mobile RNA travels between the two species and regulate methylation level of thousands… Read More »